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Global Caco-2 Permeability Assay Market Growth (Status and Outlook) 2025-2031
Sep 2025
Information and Communication Technology
Pages: 107
LPI9272
The global Caco-2 Permeability Assay market size is predicted to grow from US$ million in 2025 to US$ million in 2031; it is expected to grow at a CAGR of %from 2025 to 2031.
The Caco-2 permeability assay is a widely used in vitro method to assess the permeability of drugs and other compounds across the intestinal epithelium. Caco-2 cells are derived from a human colon carcinoma cell line and possess many characteristics of mature enterocytes, making them a suitable model for studying drug absorption in the intestine.
In the assay, Caco-2 cells are grown on a permeable membrane, forming a monolayer that mimics the intestinal epithelium. The compound of interest is then applied to the apical (luminal) side of the monolayer, and the amount that crosses the monolayer and appears in the basolateral (blood) side is measured.
The permeability of the compound is determined by calculating the apparent permeability coefficient (Papp), which takes into account the concentration of the compound on both sides of the monolayer, the surface area of the monolayer, and the time of incubation. Papp values can be used to classify compounds into different categories based on their absorption potential, such as high, moderate, or low permeability.
The Caco-2 permeability assay is commonly used in drug discovery and development to predict the oral absorption of compounds and assess their potential for drug-drug interactions. It provides valuable information on the ability of a compound to cross the intestinal barrier and reach systemic circulation, which is crucial for determining its bioavailability and efficacy.
United States market for Caco-2 Permeability Assay is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
China market for Caco-2 Permeability Assay is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Europe market for Caco-2 Permeability Assay is estimated to increase from US$ million in 2024 to US$ million by 2031, at a CAGR of % from 2025 through 2031.
Global key Caco-2 Permeability Assay players cover Creative Biolabs, Cyprotex, Creative Bioarray, Aurigene Pharmaceutical Services, Solvo Biotechnology, etc. In terms of revenue, the global two largest companies occupied for a share nearly % in 2024.
Infinity Market Research newest research report, the ?Caco-2 Permeability Assay Industry Forecast? looks at past sales and reviews total world Caco-2 Permeability Assay sales in 2024, providing a comprehensive analysis by region and market sector of projected Caco-2 Permeability Assay sales for 2025 through 2031. With Caco-2 Permeability Assay sales broken down by region, market sector and sub-sector, this report provides a detailed analysis in US$ millions of the world Caco-2 Permeability Assay industry.
This Insight Report provides a comprehensive analysis of the global Caco-2 Permeability Assay landscape and highlights key trends related to product segmentation, company formation, revenue, and market share, latest development, and M&A activity. This report also analyses the strategies of leading global companies with a focus on Caco-2 Permeability Assay portfolios and capabilities, market entry strategies, market positions, and geographic footprints, to better understand these firms? unique position in an accelerating global Caco-2 Permeability Assay market.
This Insight Report evaluates the key market trends, drivers, and affecting factors shaping the global outlook for Caco-2 Permeability Assay and breaks down the forecast by Type, by Application, geography, and market size to highlight emerging pockets of opportunity. With a transparent methodology based on hundreds of bottom-up qualitative and quantitative market inputs, this study forecast offers a highly nuanced view of the current state and future trajectory in the global Caco-2 Permeability Assay.
This report presents a comprehensive overview, market shares, and growth opportunities of Caco-2 Permeability Assay market by product type, application, key players and key regions and countries.
Segmentation by Type:
Directional Measurement from Apical to Basal
Directional Measurement from Basal to Apical
Segmentation by Application:
Laboratory
Factory
This report also splits the market by region:
Americas
United States
Canada
Mexico
Brazil
APAC
China
Japan
Korea
Southeast Asia
India
Australia
Europe
Germany
France
UK
Italy
Russia
Middle East & Africa
Egypt
South Africa
Israel
Turkey
GCC Countries
The below companies that are profiled have been selected based on inputs gathered from primary experts and analyzing the companys coverage, product portfolio, its market penetration.
Creative Biolabs
Cyprotex
Creative Bioarray
Aurigene Pharmaceutical Services
Solvo Biotechnology
XenoTech
Absorption Systems
IONTOX
Eurofins Discovery
University of Texas Southwestern Medical Center
Quintara Discovery
Bioduro-Sundia
Enamine
Merck
AxisPharm
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